circulating tumor dna (ctdna) is the cell-free dna in body fluid, such as serum, plasma, cerebrospinal fluid and synovial fluid. in the formation and development stages of the primary tumor, the tumor cell will die and wither and their dna will be freed into the blood. the ctdna in the peripheral blood of the tumor patients has a higher content than the healthy individuals. besides, the ctdna is called cell-free ctdna.
ubiopsy using next generation sequencing technology, can partly replace the traditional histology invasive biopsy. by analyzing ctdna with ngs, early detection of tumor, personalized treatment decision and supervision of prognosis can be monitored.
advanced:the illumina high-throughput sequencing system and bioinformatics analysis platform are adopted.
noninvasive:in ctdna noninvasive personalized tumor treatment genetic test, such as invasive test means as needle biopsy and operations are unnecessary.
sensitive:compared with traditional tumor markers, ctdna can truthfully reflect the progress of tumor as it is of high sensitivity.
professional:the interpretation of the test is based upon our powerful database including both the authoritative databases and the latest clinical research results.
scientists have discovered that dying tumor cells release small pieces of their dna into the bloodstream. these pieces are called cell-free circulating tumor dna (ctdna).
ctdna is derived from somatic mutations that occur in the tumor during an individual's life, ctdna is a specific cancer biomarker that can be detected, measured, and tracked.monitoring ctdna is expected to provide clinicians with faster, cheaper, less invasive ways to assess cancer patients' clinical status and response to therapy.
the ctdna is the ideal tumor marker as it can provide important information for early diagnosis, therapeutic effect evaluation, relapse supervision and prognosis judgment through gene sequencing.
ctc (circulating tumor cells) is the integrated tumor cell in blood of tumor patients, while ctdna is cell-free dna in serum or plasma. detection of cancer based on ctdna analysis is more sensitive than analysis of ctc.