新墨西哥大学生物医学phd,2011年起在美国希望之城(city of hope)从事分子药理学相关的博士后研究。拥有10年以上分子生物、细胞生物学转化研究专业背景,主要从事二代测序技术、动物疾病模型的设计以及癌症干细胞等方向的研究。构建及研发多重转录测序技术,并成功的应用于对白血病亚型预后分子标记物的识别。此外,在ctc、ctdna、个性化用药指导等方面有着丰富的临床经验。核心期刊发表论文10余篇,国际大会做专题报告数场。
scott a. ness
首席科学顾问(ngs测序技术)
scott a. ness
首席科学顾问(ngs测序技术)
美国unm新墨西哥大学癌症中心副主任、victor and ruby hansen surface癌症基因组织专家、内科学教授、“分析和转化基因组学资源共享组织”负责人;致力于癌症生物学、基因调控、造血干细胞和表观遗传学等领域的研究,先后在cell等在内的国际学术期刊发表论文五十余篇。
● ning y, zhang w, hanna d l, et al. (2016).clinical relevance of emt and stem-like gene expression in circulating tumor cells of metastatic colorectal cancer patients.pharmacogenomics journal.
● ning y, hanna dl, et al. cytokeratin-20 and survivin expressing circulating tumor cells predict survival in metastatic colorectal cancer patients by a combined immunomagnetic qrt-pcr approach. mol cancer ther. 2015 oct;14(10):2401-8
● ye zhou, eric c bolton, jeremy o jones. (2014) androgens and androgen receptor signaling in prostate tumorigenesis. journal of molecular endocrinology , 54(1), 15-29.
● hanli xu and yongtao guan (2014), detecting local haplotype sharing and haplotype association. genetics 197(3):823--838.
● ye zhou, maya otto-duessel, miaoling he, susan markel, timothy synold, jeremy jones. (2013) low systemic testosterone levels induce androgen maintenance in benign rat prostate tissue. journal of molecular endocrinology, 2013, 6(5):514743
● ye e. zhou, john o’rourke, jeremy edwards, scott ness. (2011) single molecule analysis of c-myb alternative splicing reveals novel biomarkers for precursor b-all. plos one. 2011;6(8): e22880
● anita m. quintana, ye e. zhou, janeth j penna, john p. o’rourke and scott a. ness. (2011) dramatic repositioning of c-myb to different promoters during the cell cycle observed by combining cell sorting with chromatin immunoprecipitation. plos one, 6(2): e17362.
● ye zhou, scott ness. (2011) myb proteins: angels and demons in normal and transformed cells. frontiers in bioscience 16: 1109-31